Which of the following correctly states an essential step in the function of heterotrimeric G protein function?
A) A cascade of events must occur that ultimately activate protein kinase C.
B) Binding of a hormone to a receptor must signal the exchange of GDP for GTP.
C) Binding of GTP to the receptor protein must induce a change in conformation of the receptor.
D) Binding of cAMP to the a subunit of the G protein must initiate translocation of the subunit.
E) All of the above are correct.
Answer: B) Binding of a hormone to a receptor must signal the exchange of GDP for GTP.
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