Which statement best describes the extrinsic pathway for apoptosis?

Which statement best describes the extrinsic pathway for apoptosis?



a) Caspases recognize an environmental signal and expose their death domain.

b) Death receptors recognize an environmental signal, which then leads to the activation of caspases.

c) Initiator caspases digest the nuclear lamina and cytoskeleton.

d) Executioner caspases are part of the death-inducing signaling complex (DISC).

e) All of the above are true of the extrinsic pathway.



Answer: B


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