Phenylketonuria (PKU) is an autosomal recessive disorder where afflicted individuals are incapable of metabolizing the amino acid phenylalanine, and it accumulates in nerve cells of the brain. What is the probability that a man and a woman that are both phenotypically normal, but are carriers, will have a child with PKU?

Phenylketonuria (PKU) is an autosomal recessive disorder where afflicted individuals are incapable of metabolizing the amino acid phenylalanine, and it accumulates in nerve cells of the brain. What is the probability that a man and a woman that are both phenotypically normal, but are carriers, will have a child with PKU?

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Phenylketonuria (PKU) is an autosomal recessive disorder where afflicted individuals are incapable of metabolizing the amino acid phenylalanine, and it accumulates in nerve cells of the brain. What is the probability that a man and a woman that are both phenotypically normal, but are carriers, will have a child with PKU?



A) 1/4

B) 1/2

C) 1/3

D) 1/6



Answer: A) 1/4


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