Aneuploidy, defined as an abnormal number of chromosomes, is the most common chromosomal abnormality. Which of the following events will result in Down Syndrome, an example of a disorder caused by the inheritance of an extra chromosome 21?

Aneuploidy, defined as an abnormal number of chromosomes, is the most common chromosomal abnormality. Which of the following events will result in Down Syndrome, an example of a disorder caused by the inheritance of an extra chromosome 21?

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Aneuploidy, defined as an abnormal number of chromosomes, is the most common chromosomal abnormality. Which of the following events will result in Down Syndrome, an example of a disorder caused by the inheritance of an extra chromosome 21?



A) the incorrect separation of this pair of sister chromatids during meiosis II

B) the failure of two sets of homologous chromosomes to line up properly during metaphase I

C) the nondisjunction of this set of homologues during meiosis II

D) a crossing over of genetic information of homologous chromosomes during prophase I



Answer: A) the incorrect separation of this pair of sister chromatids during meiosis II


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