To calculate plasma clearance of any substance, it is necessary to know the
A. quantity of urine produced per minute.
B. concentration of the cleared substance in the urine.
C. concentration of the cleared substance in the blood.
D. blood volume.
E. quantity of urine produced per minute, the concentration of the cleared substance in the urine, and the concentration of the cleared substance in the blood.
Answer: E. quantity of urine produced per minute, the concentration of the cleared substance in the urine, and the concentration of the cleared substance in the blood.