In E. coli replication the enzyme primase is used to attach a 5 to 10 base ribonucleotide strand complementary to the parental DNA strand. The RNA strand serves as a starting point for the DNA polymerase that replicates the DNA. If a mutation occurred in the primase gene, which of the following would you expect?
A) Replication would only occur on the leading strand.
B) Replication would not occur on either the leading or the lagging strand
C) Replication would not be affected as the enzyme primase is involved with RNA synthesis
D) Replication would only occur on the lagging strand
Answer: B) Replication would not occur on either the leading or the lagging strand
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