A researcher has designed a new drug that will block the release of certain neurotransmitters from the synaptic cleft. Which of the following reactions must be blocked by this new drug?
A) The drug binds the receptors in the postsynaptic membrane and blocks neurotransmitter binding.
B) The drug binds the presynaptic membrane greatly facilitating the rate of transverse diffusion, thus changing the composition of the membrane.
C) The drug enhances activity of SNARE proteins, thus facilitating fusion.
D) All of the above are plausible actions of this new drug.
E) None of the above is a plausible action of this new drug.
Answer: B) The drug binds the presynaptic membrane greatly facilitating the rate of transverse diffusion, thus changing the composition of the membrane.
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