Achondroplasia is a common form of dwarfism caused by an autosomal dominant mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. Two copies of the mutant gene are invariably fatal before or shortly after birth. If a person with achondroplasia marries a person of normal height, what is the probability that both their first child and second child will have achondroplasia?

Achondroplasia is a common form of dwarfism caused by an autosomal dominant mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. Two copies of the mutant gene are invariably fatal before or shortly after birth. If a person with achondroplasia marries a person of normal height, what is the probability that both their first child and second child will have achondroplasia?

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Achondroplasia is a common form of dwarfism caused by an autosomal dominant mutation in the fibroblast growth factor receptor 3 (FGFR3) gene. Two copies of the mutant gene are invariably fatal before or shortly after birth. If a person with achondroplasia marries a person of normal height, what is the probability that both their first child and second child will have achondroplasia?



A. 1/8
B. 1/4
C. 1/2
D. 1


Answer: B


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