You have discovered a protein that inhibits translation. When you add this inhibitor to a mixture capable of translating human mRNA and centrifuge the mixture to separate polyribosomes and single ribosomes, you obtain the results shown in Figure Q7-57. Which of the following interpretations is consistent with these observations?

You have discovered a protein that inhibits translation. When you add this inhibitor to a mixture capable of translating human mRNA and centrifuge the mixture to separate polyribosomes and single ribosomes, you obtain the results shown in Figure Q7-57. Which of the following interpretations is consistent with these observations?



(a) The protein binds to the small ribosomal subunit and increases the rate of initiation of translation.
(b) The protein binds to sequences in the 5' region of the mRNA and inhibits the rate of initiation of translation.
(c) The protein binds to the large ribosomal subunit and slows down elongation of the polypeptide chain.
(d) The protein binds to sequences in the 3' region of the mRNA and prevents termination of translation.


Answer: B


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