The core histones are small, basic proteins that have a globular domain at the C-terminus and a long, extended conformation at the N-terminus. Which of the following is not true of the N-terminal "tail" of these histones?

The core histones are small, basic proteins that have a globular domain at the C-terminus and a long, extended conformation at the N-terminus. Which of the following is not true of the N-terminal "tail" of these histones? 



(a) It is subject to covalent modifications.
(b) It extends out of the nucleosome core.
(c) It binds to DNA in a sequence-specific manner.
(d) It helps DNA pack tightly.


Answer: C


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